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KMID : 0985520150200020078
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Korean Journal of Pancreas and Biliary Tract
2015 Volume.20 No. 2 p.78 ~ p.82
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A Case of Pancreatic Cancer with Markedly Elevated Serum Immunoglobulin G4
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Kwon Young-Seok
Moon Sung-Hoon
Kang Ho-Suk
Lim Hyun
Choi Nan-Young
Kim Soon-Young
Kang Dong-Hoon
Kim Jong-Hyeok
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Abstract
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Differential diagnosis between autoimmune pancreatitis (AIP) and pancreatic cancer is often difficult due to similar clinical manifestations and radiological findings. Serum immunoglobulin G4 (IgG4) is a marker to differentiate AIP from pancreatic cancer. Although serum IgG4 can be elevated in 10% of patients with pancreatic cancer, most of serum IgG4 elevation in pancreatic cancer is limited within two times of upper normal limit. Herein, we report a case of pancreatic cancer with markedly elevated serum IgG4 over six times of upper normal limit that needed steroid trial to differentiate from AIP.
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KEYWORD
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Serum immunoglobulin G4, Pancreatic cancer, Autoimmune pancreatitis
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